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Regarding Johnnes', I would say that it IS obvious, same symptoms as cattle. They get the runs and they drop body weight very fast, even though they still eat. This is after worms and other intestinal problems have been ruled out. We had what seemed to be this disease affect a friend's small flock of barbado sheep that were being boarded at our place. Our wool sheep have never shown the slightest sign of illness and it's been over 3 years now. Johnnes' is very difficult to diagnose, the sick sheep came from a flock that was tested over and over again, and they got 1 positive result after many negative ones.