Not unless the doe needs them. Watch for temp and infection, and THEN treat. i check does often, in fact, i had three very difficult births this year, I was into the uterus far past the cervix and did not have to treat with antibiotics as the does did not get an infection. Just going into the vagina is not going to necessarily make the doe ill. It usually self-cleans. Overuse of antibiotics is never a good thing. besides, the effects of antibiotic use on the rumen can be worse than what you are trying to prevent. Why upset rumen flora when there is no problem?JRF said:After going inside you are going to want to start her on a round of antibiotics also.