I am wondering how large of an animal can be killed with a .45 cal. semi-auto pistol. Would a person be able to kill a couger with this caliber? How effective would a .40 S&W caliber semi-auto be on a couger? I have read and have been told that a .357 Magnum is a good caliber for a couger but other than a .357 Sig that caliber seems to come only in a revolver. I am not interested in a .44 Mag and beyound. You good old boys seem to have lots of outdoor experiences and I would be very interested with what you would have to say about this subject.