I keep epi pulled and in the barn with me anytime I give shots, I have never had to use it on my own stock.
It's instant when a goat goes down, there will be no waiting
You may see shock when vaccinating, but likely this would only be with an antitoxin..you may see shock when giving antibitotics and even in does who previously have had the same drug before. I honestly think most reactions come from dragging the needle with the med being squirted in, through a blood vessel.
I keep everything in the fridge, this extends the date it needs to be thrown out, keeps it out of the humidity and the light. Bo-se is just a mineral I would not throw it out, I would use it, I would throw it out had you said it was a vaccine.
I always redo vaccinations it's simply easier and cheaper than taking the word of someone else. So give the first shot, give the 2nd shot 21 days later and leave it at that, it is also going to put you pretty durn close to her needed shot of 3 weeks before she kids if she is due anytime in March.
Yeah you will have to wait to see what happens with the doe. Being a Lamancha just because you haven't see a heat this past couple months really doesn't mean alot either. And if she has been in milk before it is near impossible to tell from her udder if she is really bred. Now if she is a young doe never bred before, you should be seeing obviously udder formation, if not seing it for sure feeling it. I took all my girls for a walk in the woods this last weekend, and you can feel everyones udder, and we are due the end of Feb to mid March.
Oh...and my neighbors next door, put a lovely grape vine in about 1 foot away from our fence...a fence they know goats live in, I hope they don't expect many grapes or leaves to be growing on that pretty vine

Vicki