
08/05/12, 11:31 AM
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Caprice Acres
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Join Date: Mar 2005
Location: MI
Posts: 11,231
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There are different biotypes that infect animals. Goats/sheep get nitrate negative. Horses get nitrate positive. Cows get a mix of both, and cultures are heterogeneous for both biotypes. Goats cannot get CL from horses, or vice versa. Sheep can and often infect goats (and vice versa) with CL. Cows can be a source of infection.
Quote:
Etiology and Pathogenesis
C pseudotuberculosis is a gram-positive, facultative, intracellular coccobacillus. Two biotypes have been identified based on the ability of the bacteria to reduce nitrate: a nitrate-negative group that infects sheep and goats, and a nitrate-positive group that infects horses. Isolates from cattle are a heterogeneous group. All strains produce an exotoxin called phospholipase D that enhances dissemination of the bacteria by damaging endothelial cells and increasing vascular permeability. The bacterium has a second virulence factor, an external lipid coat, that provides protection from hydrolytic enzymes in host phagocytes. Replication of bacteria occurs in the phagocytes, which then rupture and release bacteria. The ongoing process of bacterial replication, followed by attraction and subsequent death of inflammatory cells, forms the characteristic abscesses associated with CL.
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http://www.merckmanuals.com/vet/circ...denitis&alt=sh
There is NOT enough information out there to discuss what biotypes rabbits, fowl, deer, and other animals get - it is simply so uncommon that it's not worth it to do studies and spend money on it. Horses, cows, sheep, and goats have known biotypes that they seem to exclusively get or do not get. I've tried looking in the past to see what kind deer get, and couldn't find info then. I'm just the kinda person that gives it another try on a fairly regular basis though.
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Dona Barski
"Breed the best, eat the rest"
Caprice Acres
French and American Alpines. CAE, Johnes neg herd. Abscess free. LA, DHIR.
Last edited by mygoat; 08/05/12 at 11:45 AM.
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